Wednesday, August 18, 2010

MICROBICIDE GEL SLASHES WOMEN'S RISK for HIV

Dearest people in the fight against HIV: Huge News.
The CAPRISA Project, at the 2010 International AIDS Conference in Vienna, has come out as the first ever successful "proof of concept" that a microbicide gel (in topical, vaginal application) can effectively prevent HIV transmission in women. YES.

And guess who was a major part of the CAPRISA Team alongside South African Doctors (Husband and Wife Team Drs. Abdool-Karim) and Participants?
UNC Center for AIDS Research principal partner FHI (Family Health International: http://fhi.org/)
and
The UNC Center for AIDS Research's own Dr. Angela Kashuba, of the CPAC Core (Clinical Pharmacology and Analytical Chemistry: http://cfar-cpacc.unc.edu/ is their brand new website!)

This is a FIRST in the fight against AIDS, and comes after a long battle to put protection against HIV transmission into women's hands. Most women had 39% efficacy when using the gel, with some experiencing up to 54% efficacy in preventing sexual transmission of HIV when topically applying the microbicide, which concentrates Tenofovir, an Anti-Retroviral Drug (ARV) given by Gilead Pharmaceuticals, into a gel form women can use vaginally before and after intercourse. Check out the press here below (it is epic, and rightfully so).

Also be sure to look out for our upcoming CENTER FOR AIDS RESEARCH DOCUMENTARY which will feature footage of the standing ovation given to the Caprisa Team at the International AIDS Conference 2010 in Vienna, when presenting their findings (where you'll see our own Dr. Angela Kashuba presenting beautifully on the panel, about the #s and understandings of how the drugs "work" in the body).

Encouraged and heartened by all this hard work
from many heroic minds, efforts and visions come true in collaboration 
(that is the spirit of the UNC CFAR, and of this CAPRISA project in which it so meaningfully took part), 
Marie and the  
UNC CODE Office


CAPRISA 004 Media Coverage Highlights
 July 19-22, 2010
New York Times — Study Offers Two Paths To Cut H.IV. Rate For African Women Celia Dugger
(with additional reporting by Donald McNeil) 
 Wall Street Journal — Gel Cuts AIDS, Herpes Risk For Women Mark Schoofs and Peter Wonacott
The Times Live — Gel scores in HIV fight Claire Keeton
Health-e — Massive Leap Forward for HIV Prevention Kerry Cullinan
Agence France-Presse — Standing ovation for HIV gel breakthrough at AIDS forum Richard Ingham
Los Angeles Times — Studies Show Promise in Curbing AIDS in Africa Thomas H. Maugh II
Washington Post — Gel found to reduce AIDS risk in women David Brown
Science — At Last, Vaginal Gel Scores Victory Against HIV Jon Cohen
Associated Press — Anti-AIDS Gel Helps Prevent Infection, Study Finds Marilynn Marchione
Reuters — AIDS Gel With Gilead Drug Protects Women In Study  Maggie Fox, Deena Beasley, Kate Kelland
Aidsmap.com — Microbicides can work, CAPRISA trial shows, but more trials needed before approval Gus Cairns
IRIN PlusNews — Microbicides - from results to reality
Al Jazeera English — Gel 'helps prevent' HIV infection
NBC Nightly News — Study: Gel a "Game-Changer" in HIV Prevention
Voice of America — CAPRISA 004 Discovery Marks Historic Day in HIV Prevention Research
NTV Kenya — Gel of Hope
BBC News —Vaginal gel 'slashes HIV risk' in South African tests
PBS News Hour — Study Reveals Potential Breakthrough for Reducing HIV Among Women
WUNC RADIO — State of Things: Progress in the HIV/AIDS Fight

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